- Open Access
Maximum walking speeds obtained using treadmill and overground robot system in persons with post-stroke hemiplegia
© Capo-Lugo et al.; licensee BioMed Central Ltd. 2012
- Received: 26 January 2012
- Accepted: 1 October 2012
- Published: 11 October 2012
Previous studies demonstrated that stroke survivors have a limited capacity to increase their walking speeds beyond their self-selected maximum walking speed (SMWS). The purpose of this study was to determine the capacity of stroke survivors to reach faster speeds than their SMWS while walking on a treadmill belt or while being pushed by a robotic system (i.e. “push mode”).
Eighteen chronic stroke survivors with hemiplegia were involved in the study. We calculated their self-selected comfortable walking speed (SCWS) and SMWS overground using a 5-meter walk test (5-MWT). Then, they were exposed to walking at increased speeds, on a treadmill and while in “push mode” in an overground robotic device, the KineAssist, until they were tested at a speed that they could not sustain without losing balance. We recorded the time and number of steps during each trial and calculated gait speed, average cadence and average step length.
Maximum walking speed in the “push mode” was 13% higher than the maximum walking speed on the treadmill and both were higher (“push mode”: 61%; treadmill: 40%) than the maximum walking speed overground. Subjects achieved these faster speeds by initially increasing both step length and cadence and, once individuals stopped increasing their step length, by only increasing cadence.
With post-stroke hemiplegia, individuals are able to walk at faster speeds than their SMWS overground, when provided with a safe environment that provides external forces that requires them to attempt dynamic stability maintenance at higher gait speeds. Therefore, this study suggests the possibility that, given the appropriate conditions, people post-stroke can be trained at higher speeds than previously attempted.
- Overground walking
- Maximum walking speed
Individuals post-stroke present an array of changes to neuromuscular system functions such as muscle weakness, impaired proprioception, abnormal muscle activation patterns, and impaired postural control. The different combinations of these and other altered body functions result in limitations in functional mobility, such as reduced gait speed. After stroke, most patients walk at speeds that range from approximately 0.2 m/s to 0.8 m/s [1–4], when asked to walk at a comfortable pace; this comfortable pace will be referred to as self-selected comfortable walking speed (SCWS) from this point forward. These velocities are significantly lower than the SCWS exhibited by age-matched individuals (1.3 m/s to 1.4 m/s) [3–5]. Also, when persons post-stroke were encouraged to walk at their self-selected maximum walking speed (SMWS) they achieved walking speeds from 0.3 m/s to 1.3 m/s [1–3, 6]. This suggests that the post-stroke population has limited capability to increase their walking speed to reach higher functional levels because of the real threats to tripping, losing balance, and/or falling, In contrast, non-neurological impaired individuals are able to transition to locomotor states that allow them to achieve very fast speeds rather than fall .
Recently, new assessments and interventions targeted at the modulation of gait speed after stroke have incorporated testing and training at fast walking speeds as part of their research and training protocols [4, 8–16]. In general, these studies suggest that the analysis of fast walking speed is an important tool to: 1) assess motor impairments [4, 11], 2) define and describe biomechanical behaviors at these speeds [8–10, 15, 16], and 3) challenge patients during training [10–15]. In fact, analysis of gait during fast walking speeds has resulted in the identification of different kinematic and kinetic factors, such as impaired power generation . Additionally, speed-dependent training studies have resulted in significant increases in gait speeds, improved coordination and apparent decreases in step variability [10–16]. However, individuals who have had a stroke do not achieve the functional levels that they had prior to the injury, even after extensive rehabilitation. In the abovementioned research studies, the methods for determining fast walking speed were dependent on safety when individuals were not wearing a harness, or on the participants’ self-determination of walking speed; thus defining the tested speeds as fastest-comfortable or fastest-possible speed. These methods do not allow for a conclusion on the fastest possible speed an individual post-stroke can reach because no study asked individuals to walk beyond their self-selected or perceived maximum walking speed. Therefore, to our knowledge, no study has explicitly tested the limits of the fastest possible gait speeds that can be achieved in persons with post-stroke hemiplegia.
In order to achieve faster walking speeds, non-impaired individuals increase cadence and/or step length, decrease length of stance phase and increase duration of the swing phase, in a symmetric manner . After stroke, individuals show an ability to modulate the abovementioned spatiotemporal parameters [9, 18, 19], but present with asymmetry between the paretic and non-paretic lower extremities [20–23]. For example, asymmetry consists of prolongation of the duration of stance phase and step length in the non-paretic side, as well as a reduction of the swing time in the non-paretic lower extremity. These deviations have been associated with walking speeds in this population, where walking speed is reduced according to the severity of the deviations . Recently, studies where spatiotemporal parameters have been tested at fast walking speeds suggest that high walking speed is not detrimental to the gait pattern and could potentially reduce gait deviations [16, 25]. However, to date no study has tested the limits of the possible speeds that are achievable after stroke and the associated changes to spatiotemporal parameters.
Also, attaining fast walking speeds requires control over the body’s dynamic stability; i.e. the capacity of the neuromuscular system to counteract or prevent a fall during movement [26, 27]. In mechanical terms, in order to increase walking speed, rapid changes to the center of mass (CoM) position, CoM velocity, and body momentum are needed . These changes require equally rapid adjustments of the base of support (BoS) in order for one to avoid falling. Researchers have proposed that falls are avoided by keeping the CoM within the feasible stability region (FSR) and margins of stability (MoS) . The FSR is an area within which the neuromuscular system has the capacity to avoid falling by attaining the necessary adjustments. The MoS refers to the boundaries of the FSR beyond which a fall would occur. These variables measured during walking at different speeds, demonstrated that dynamic stability during walking is speed-dependent [26, 29, 30]. In general, these studies show a reduction of dynamic stability at high walking speeds; likewise, individuals show greater dynamic stability at slow walking speeds.
With this study, we ask the question: how fast can individuals with post-stroke hemiplegia walk when prompted to the margins of stability at very high speeds? In other words, what are the top speeds that individuals can achieve before they become unstable and lose balance? This assessment of walking beyond SMWS could provide novel insights regarding the capabilities of this population to adapt current neuromuscular mechanisms into more challenging walking tasks. We hypothesized that these participants will be able to walk at higher speeds, compared with overground SMWS, when provided with external forces that assists them to attempt higher gait speeds. To test this hypothesis, we selected two alternate modes for providing assistance with external forces: 1) motorized treadmill walking and, 2) “push mode” walking, generated by an overground robotic device (i.e. the KineAssist, Figure 1). Also, we expected to find increases in step length and cadence according to increments in speed, as well as a top, limiting speed which would consistently result in a loss of balance.
Characteristics of subjects
Paretic Side (L/R)
Average SCWS (m/s)
Criteria for Analysis Exclusion
Used treadmill harness for body weight support
Unable to walk without cane during overground and treadmill walking
Leaned backward in the robotic device
Refused to be tested at increased speeds on both devices
Refused to be tested at increased speeds while in the treadmill
Unable to keep feet within the treadmill belt width
Refused to be tested at increased speeds on both devices
Refused to be tested at increased speeds while in the robotic device
Unable to keep feet within the treadmill belt
Abbreviations and definitions and abbreviations of the walking speeds measured
Self-selected comfortable walking speed
Overground walking speed when the individual was instructed to “walk at your normal comfortable speed”
Average self-selected comfortable walking speed
Comfortable walking speed selected by the participant during an overground 5-MWT average across 3 trials
Self-selected maximum walking speed
Overground walking speed when the individual was instructed to “walk as fast as you safely can”
Average self-selected maximum walking speed
Maximum walking speed selected by the participant during an overground 5-MWT average across 3 trials
Top walking speed
Highest speed that the individual could reach in a single trial overground, on the treadmill and in the robotic device
This 5-MWT test was conducted on an 8-meter walkway. Time and number of steps were recorded from the middle 5 meters and the first and last 1.5 meters were discarded in order to account for acceleration and deceleration phases during gait. Participants were asked to complete the overground 5-MWT by walking without any assistive device at their SCWS and SMWS, three times for each speed. Inability to perform the overground 5-MWT walk without any assistive device resulted in exclusion from the experiment. Then, we calculated the average SCWS and the average SMWS walking speeds.
“Push mode” graded 5-MWT
During the “push mode” 5-MWT, participants walked over the same 8-meter walkway as the one described above in the overground 5-MWT. However, in this portion of the study, participants executed the protocol while attached to a robotic device called the KineAssist Gait and Balance Training System™. This robotic device consists of a torso and a pelvis harness attached to a mobile robotic base (Figure 1). This device has been described extensively elsewhere [31, 32]. It was used in this experiment for two reasons; to provide a safe walking environment, especially at faster speeds, and to “push” the participant at a variety of fixed walking speeds. Regarding safety, if a person loses balance at any point while they are walking in the device, the device will detect the fall as a drop in the height of their pelvis, will catch the person in the harness system and will simultaneously cease from moving forward. In the “push mode” the mobile base was driven from rest to a fixed, target speed over a short acceleration period (1–2 seconds) so that it pushed the individual to walk at that target speed. The subject’s goal during the task was to keep up with the push and to progress with walking. Subjects were strongly encouraged to maintain normal walking kinematics and were discouraged from leaning back and letting the device carry them forward, any trial where this may have occurred was not used for data analysis. Participants underwent a short familiarization process with the robotic device that consisted of: practice of self-induced falls to establish trust with the safety of the system, free walking to get accustomed to the torso and pelvis harness, and walking in the “push mode” at comfortable speeds. Due to the novelty of the system, we asked participants to decide when they felt comfortable moving in the robotic device and then we concluded the familiarization process.
Participants began the “push mode” graded 5-MWT at their SCWS, as calculated from their overground 5-MWT. After each successful trial, the speed was increased by 0.2 m/s until the participant reached a speed that resulted in 3 consecutive failure trials (e.g. loss of balance resulting in a drop of 3 inches) resulting in loss of balance (the system catches the individual), or refusal to attempt a faster speed. Once 3 consecutive failures were observed, the speed was reduced until 3 successful trials were observed at some consistent speed. This successful speed level was recorded as the top walking speed (TWS) in the “push mode”. A maximum possible test speed of 2 m/s was established a priori to ensure a safe environment for the participants and ensure that the device did not become unstable which may happen with excessively high travel speeds. If a participant reached the maximum test speed of 2.0 m/s and no failure was observed then 2 additional trials were attempted and, if successful for three attempts, then 2 m/s was the TWS recorded for that participant.
Treadmill graded 5-MWT
During the treadmill 5-MWT, participants were placed in a body harness that was attached to an overhead arch (Biodex Unweighting System) that provided a safety catch in case of a fall. This device did not provide any body weight support during the walking test and any trial where the participant was observed using the system for body weight support was discarded from data analysis. In order to perform the graded 5-MWT on the treadmill (Biodex Gait Trainer 2TM) belt a 5-meter distance was measured on the belt and tracked manually. Participants started walking along with the treadmill belt, but the acceleration phase was determined by the treadmill belt, since the test was started once the treadmill reached the desired speed.
The goal for the treadmill graded 5-MWT was similar to the “push mode”. Participants started the test at their calculated SCWS and the speed was increased by 0.2 m/s until the participant attempted a speed where they had 3 consecutive failures or reached the maximum test speed (2.0 m/s). A failure in the treadmill graded 5-MWT was determined by: an inability to maintain an appropriate walking posture (leaning forward, backwards or resting on the harness system), grabbing the handrails, an inability to walk at the set speed resulting in a fall (the system catches the individual), an inability to maintain the base of support (the feet) within the treadmill belt width, and/or refusal to attempt a faster speed. Once 3 consecutive failures were observed at a particular speed, the speed was reduced until 3 successful trials at that speed were accomplished. This final test speed was recorded as the TWS in the treadmill 5-MWT.
Characterization of force produced at the pelvis (mini-experiment conducted with nonimpaired, younger participants)
In order to test whether subjects generate the same propulsive forces when freely moving at their desired speed versus when forced during the “push mode”, we characterized the force supplied at the pelvis onto the robot interface by the participants while walking in the robotic device. The KineAssist, without the “push mode”, is driven by a servomechanism that directs the robot position according to the forces detected from the subject at the pelvic mechanism [31, 32]. Horizontal force sensed at the pelvis, through load cells located at the pelvic mechanism, was recorded from the robotic device at 100 samples/sec using the EKG data acquisition system. The force supplied at the pelvis was normalized to duration of the steps, and an average across trials for each individual was performed.
Seven healthy, young (less than 40 years old), nonimpaired individuals agreed to walk in the robotic device during “push mode” (the robotic device pushes the individual to walk at a specified speed) and non-“push mode” (the robotic device moves along with the individual at the individual’s selected speed). All trials were conducted on a 14-meter walkway, in which data was only recorded from the middle 10 meters and the first and last 2 meters were discarded. Subjects initially walked in the non-“push mode” and freely chose slow, comfortable, and fast walking speeds, repeated for three trials each. Then, individuals walked in the “push mode” at matched slow, comfortable, and fast walking speeds, presented in random order.
Data Processing and Analysis
During each trial, the time and number of steps were recorded and the walking speed, average step length, and average cadence were calculated. Speed was determined by dividing the 5-meter distance by the recorded time needed to finish the distance and reported in m/s. Average step length refers to the 5-meter distance divided by the number of steps recorded and reported as m/step. Average cadence was calculated by dividing the number steps recorded by the time needed to complete the 5-meter distance and reported as steps/sec.
Average SCWS refers to the comfortable walking speed selected by the participant during an overground 5-MWT average across 3 trials. Average SMWS refers to the maximum walking speed selected by the participant during an overground 5-MWT average across 3 trials. In both the treadmill walking and “push mode” walking, the comfortable and maximum walking speeds were matched to the closest value of overground SCWS and SMWS. The TWS was defined as the highest speed that the individual could reach in a single trial (see Table 2). Also, the reported average cadence and average step length (not accounting for the asymmetry in hemiparetic step length) during a specific velocity were the values associated with the corresponding speed in each condition.
In order to test the hypothesis that chronic stroke survivors will be able to walk at higher speeds in “push mode” and treadmill walking when compared with SMWS overground, we performed repeated measures ANOVAs with post-hoc Tukey-Kramer analyses (significance selected if adjusted p<0.05). This statistical analysis included testing the differences during each walking condition (overground, treadmill, and “push mode”) for speed (SCWS, SMWS, TWS), and average step length and cadence. Linear regression analyses were used to test for relationships between: 1) average step length or cadence (dependent variables) and walking speed (independent variable) during treadmill and “push mode” walking, and 2) walking speed (on the treadmill and “push mode”) to Fugl-Meyer and Berg Balance Scores. Also, force profiles were graphed in order to visualize the force exerted at the pelvis by healthy participants during the different walking conditions. All statistics were performed using StatView Software (Version 5.0, SAS Institute, Cary, North Carolina) with an α level of 0.05.
Testing situations during “push mode” and treadmill walking that resulted in inclusion or exclusion from statistical analyses
Num. of participants
Able to walk at 2 m/s without losing balance
Loss of balance at 2 m/s or less
Loss of balance threshold not reached due to:
Participant refused to increase walking speed
Total number of participants:
Stroke survivors were able to walk at a grouped average self-selected comfortable speed (SCWS) while overground of 0.67 ± 0.04 m/s. When trials that were selected to match similar walking speeds in the other two walking conditions (“push mode”: 0.66 ± 0.04 m/s; treadmill: 0.67 ± 0.04 m/s; p > 0.05), as shown in Figure 2A, significantly longer average step lengths (Figure 2D) were observed overground when compared to push mode and treadmill walking (overground: 0.45 ± 0.03 m/step; “push mode”: 0.40 ± 0.02 m/step; treadmill: 0.40 ± 0.03 m/step; p<0.05). Also during trials that were selected to matched SCWS, significantly lower average cadences (Figure 2G) were observed overground (1.42 ± 0.05 steps/sec) when compared to “push mode” (1.57 ± 0.07 steps/sec) and treadmill walking (1.58 ± 0.05 steps/sec) (p<0.05).
Likewise, when the self-selected maximum walking speeds (SMWS) overground were chosen to closely match the other two conditions (Figure 2B; overground: 1.10 ± 0.09 m/s; “push mode”: 1.09 ± 0.09 m/s; treadmill: 1.05 ± 0.08 m/s; p > 0.05), the results for average step length and average cadence at SMWS (Figure 2E and Figure 2H, respectively) were similar to those obtained during SCWS.
Linear regression analyses results for step length or cadence versus walking speed increments during “push mode” walking and treadmill walking
In terms of balance loss experienced by participants, the number of individuals who experienced a loss of balance was higher in the treadmill and the number of individuals reached the predetermined top speed was higher in the “push mode” (Table 3). Individuals who refused to increase walking speed or were unable to use the systems properly were classified separately and were excluded from the statistical analyses that required use of top walking speeds (TWS) in the “push mode” and on the treadmill (see Table 1 and 3 for more details). Refusal to increase walking speed and inability to use the devices properly impeded the researcher’s ability to determine the individuals’ TWS, previous to a loss of balance. Also, higher number individuals were unable to use the treadmill properly but a similar number of individuals refused to increase their walking speed on both conditions.
This study investigated the capability of individuals with chronic stroke to attain faster walking speeds than their self-selected overground maximum walking speed, when using a treadmill or when pushed overground using a robotic device (“push mode”). The results showed that these individuals were capable of walking significantly faster in treadmill and “push mode” walking compared with their overground self-selected maximum walking speed. Moreover, in many cases they were able to match the top speed limit of the robotic device (2.0 m/sec), indicating that they may have been capable of moving at an even higher velocity. In terms of spatiotemporal parameters, as participants walked under progressively faster conditions, they were able to increase both average step length and average cadence until a maximum average step length was reached and then significant increases in cadence were needed to match speeds. We discuss each of these key results below.
Both conditions, treadmill and “push mode” walking, permitted participants to attain significantly faster walking speeds as compared to their self-selected maximum walking speed overground. This result reaffirms that individuals post-stroke are able to, at least, match their overground walking speeds when walking on a treadmill. In the case of this experiment, when walking in the robotic device; the results are consistent with those that were demonstrated by studies aimed to determine differences between overground and treadmill walking at matched speeds [16, 33–39]. It is important to note that in those studies, as in this experiment, walking speeds on the treadmill were determined by the researcher. However, studies where post-stroke individuals self-select their walking speeds on the treadmill revealed that individuals choose speeds that are significantly slower than those self-selected overground [9, 40]. Our current study showed that individuals were not only able to match their overground walking speeds, but also had the capability to go beyond those self-selected walking speeds overground.
The ability of individuals to attain faster walking speeds during treadmill and “push mode” walking might be due to common features between the two devices. For instance, both devices provided rhythmically constant external cues at fixed speeds allowing for a more stable and continuous walking pattern than during a self-selected walking speeds. On the treadmill, several experiments in people post-stroke have demonstrated a more symmetrical kinematic gait pattern and decrease step-to-step variability compared to overground walking [33, 34]. These more symmetrical walking patterns might be associated with the capability of individuals to reach faster walking speeds. In the robotic device, the only evidence available indicates that no kinematic alterations are observed with functional activities [41, 42]. In this way, the device’s predetermined speed requires individuals to choose only those appropriate walking strategies that serve to avoid falling. Our results showed that participants had longer step lengths and slower cadences during overground walking compared to the other two conditions (treadmill and “push mode”) of matched walking speeds. These results have been extensively demonstrated for the treadmill versus overground walking [9, 12, 33, 35].
In addition, participants wore a safety harness during both walking conditions. We propose that, by wearing a safety harness, participants experienced decreased levels of fall-related anxiety (decrease fear or concern of falling) which allowed individuals to appraise their own walking capacities at more challenging and faster speeds. In older individuals, studies suggest that anxiety related to falls is eliminated or reduced by wearing a harness . Also, spatial and temporal parameters are affected not only by physiological constraints, but also by psychological demands [44–46]. Stability-challenging tasks (i.e. walking on elevated or narrow walkways) while in conditions that alter anxiety (i.e. dual tasks or dimmed light) induced decrease walking speeds, shorter steps, decrease cadence, and increase time in double limb support. These studies support a multidimensional model of fear of falling, where fear and anxiety result from an individual’s appraisal of his or her own abilities to maintain balance in combination with other contributors such as falls history . Even though this model has been based on data and experiments performed in older individuals it could be extended to other populations, such as stroke survivors. In the context of this experiment we propose that, by wearing a safety harness, participants experienced decreased levels of fall-related anxiety which allowed individuals to appraise their own walking capacities at more challenging and faster speeds. However, it is important to note that four participants were unwilling to increase their walking speeds in order to avoid experiencing a loss of balance. These participants explicitly stated that they were fearful, apprehensive, or anxious about walking at faster speeds, despite repeated demonstrations that the device was capable of catching them and preventing harm during the experiment. In the case of this group of participants, we think that fear of falling was not reduced, regardless of the use of a harness. In the multidimensional model of fear of falling mentioned above, fear of falling results from an individual’s appraisal of his or her own abilities to maintain balance . This appraisal has three components: physiological, behavioral, and cognitive; all of which could be affected after a stroke. For example, the physiological component is appraised when changes to locomotor control after stroke can negatively impact balance and gait performance. Also, previous falls could lead to the development of the “post-fall” syndrome (i.e. avoidance of activity due to excessive fear of falling) or negatively affecting the cognitive component [47–49]. In our current experiment, none of these components were empirically tested, but our experimental set-up was designed to test the limits of the neurophysiological system. In other words, we asked individuals to increase their walking speed until a loss of balance or a fall was experienced which we interpreted as the fastest speed that the neuromechanical system could accommodate. Thus, we expected individuals to experience some level of fear or concern of falling due to the physiological and cognitive loads imposed to individuals when exposed to this environment in a single session. In summary, the group of participants that were unwilling to attain faster walking speeds represented a subgroup of the post-stroke population in which fear of falling causes an avoidance of participation, whereas in the group of participants that were able to attain faster walking speed, fear of falling was reduced by wearing a harness and demonstration of the ability of the systems to catch people and avoid harm. Also, we propose that the individuals who achieved faster walking speeds were being asked to react to predetermined, stable, and continuous speeds while in provided with a safe environment, in contrast to situations where they are asked to self-select both walking speed and pattern without necessarily providing increased safety assurances.
Participants reached significantly faster speeds during treadmill walking than overground walking, but those speeds were not as fast as those attained in the “push mode” of the robotic device. This result might be influenced by the different biomechanical constraints imposed by each walking environment. Previous investigations that compared treadmill and overground walking have found that, regardless of age, healthy individuals showed minimal changes in spatiotemporal and kinematic gait parameters, but variables such as patterns of muscle activation differ slightly [35–37, 50]. In stroke survivors, the evidence suggests even more differences in kinematic and kinetic parameters in treadmill versus overground walking [33, 34, 38, 39]. These studies have shown that during treadmill walking individuals present immediate changes in joint angles, muscle activity, and spatiotemporal parameters that result in more consistent and symmetrical walking patterns. These changes have been attributed mostly to the constraints imposed by the treadmill. For example, when the non-paretic leg is in stance phase, and the treadmill belt moves backwards, the paretic leg is forced to perform a timely swing to maintain the center of mass inside the margins of stability to avoid falling . In this way, not only mechanical changes are observed but also alterations in muscle activity that result in more appropriate walking behaviors . Also, the changes observed in the spatiotemporal parameters seem to be influenced by speed, as demonstrated by several studies [15, 16, 33]. Our results agree with previous investigations that the mechanical constraints of the treadmill induce mechanical and neuromuscular changes that allow individuals to acquire walking patterns that adjust to faster speeds.
Participants reached their greatest walking speeds during “push mode” and in many cases were able to match the top speed limit of the robotic device (2.0 m/sec), which indicates that they may have been able to walk at even greater speeds. We propose that these results are due to a combination of factors, such as a decreased fear of falling, and biomechanical constraints imposed by the robotic device, among other factors. The first two factors mentioned (fear of falling and speed control) are common to treadmill walking and explained above. On the other hand, the constraints imposed by the robotic device are different from those during treadmill walking. During “push mode” walking, the robotic device moves along with the individual providing a safe overground walking environment, but also allows for control of walking speed. Thus, when the device was set to move at a specified speed, individuals were required to advance their lower extremities, under their own volition and in response to a forward push provided by the device, in order to keep up with the device’s velocity and avoid falling. In other words, the robotic device “pushed” individuals to walk at specified speeds by controlling the velocity and position of the individual’s center of mass. Contrary to the treadmill belt, where the margins of stability are controlled by moving the feet, this pelvic mechanism controls the velocity of the individual’s center of mass. Additionally, the robotic device’s design allowed participants to walk overground which provided congruent sensorimotor information regarding body progression and displacement; contrary to treadmill walking where individuals experience conflicting visual, proprioceptive and vestibular information. Also, the robotic device did not provide assistance with stability since it was developed to allow full degrees of freedom about the hip, pelvis, and trunk so as to challenge individuals to maintain balance . In detail, this robotic device consists of a torso and a pelvis harness attached to a mobile robotic base. The pelvic harness has six degrees of freedom that allow individuals to move in all directions while walking. Both harnesses have a transparent Safety Zone in which the individual can move without any assistance or hindrance from the device. At the boundary of this range the trunk support implements a compliant constraint which catches the patient when he or she loses balance . The combination of these characteristics result in an environment that is safe for attaining fast walking speeds but also similar enough to normal overground walking that the individual is not required to use a different gait strategy than what he or she normally uses for ambulation.
Also, in the mini-experiment with non-impaired subjects reported here, during the “push mode” walking individuals generated less force than at equivalent speeds while in the robotic device without being “pushed”. This reflects decreased force generation to develop forward velocity, allowing subjects to achieve a given velocity with lesser effort. This important finding relates to the determinants of walking speed in post-stroke individuals previously reported. Researchers found a positive correlation between muscle strength and walking speed, both at comfortable and maximum walking speeds [3, 4, 51–62]. In terms of comfortable walking speed, most studies agreed that the strongest predictor, of walking speed after stroke, was hip and ankle power generation on the paretic leg during the pre- and initial swing phases of the gait cycle [4, 51, 55, 56, 59]. In terms of maximum walking speed, the strongest predictors included decreased strength in the hip flexors [4, 51, 55, 57] and ankle plantar flexors [3, 4, 51, 54, 55, 57, 59, 61]. Moreover, in the post-stroke population individuals who present a lower functional level, both ankle and hip power generation did not increase with increased voluntary walking speed as they do in controls [4, 56]. If the decreased force generation observed in healthy individuals, in this experiment, also occurred in the post-stroke individuals that we studied then we can infer that the robotic device’s “push mode” provided assistance while walking. In other words, the robotic device provided the necessary force to achieve those speeds; thus compensating for individuals’ impairments. This indicated that individuals with impaired power generation would be able to achieve greater walking speeds in the “push mode”. The specific mechanisms by which this assistance occurred in this experiment are unclear, but will be addressed in future studies.
During both the treadmill and “push-mode” conditions, participants increased their average step length and average cadence until a plateau was reached by the average step length and subsequently significant increases in cadence were observed. These results are consistent with previous studies that showed changes in spatiotemporal parameters with increments in speed [9, 16, 33], implying that post-stroke individuals have the capacity to modify their current walking pattern in order to increase walking speed. Our results suggest that once individuals stopped increasing step length, increments in cadence were the only available modification to the current walking pattern. However, the changes in spatiotemporal parameters observed differ between researchers, as well as the definition of “fast speeds”. For example, during treadmill walking Bayat el al. found increased step length but not cadence , Tyrell et al.  found longer step lengths, and Brouwer et al.  a combination of different kinetic and kinematic factors to attain faster walking speeds [16, 33]. Our results showed that participants had longer step lengths and slower cadences during overground walking compared to the other two conditions (treadmill and “push mode”) at matched walking speeds; similar to previously published data [9, 33–35]. However, our results also showed that when these individuals were prompted to walk at faster speeds than their maximum overground walking, their step lengths increased to match those of maximum overground walking and subsequently, only increased cadence was observed. These results suggest that once the limit in step length is reached, increments in cadence are the only available modification to the current walking pattern. Therefore, we propose that at fast walking speeds step length became a limiting factor to achieve faster speeds during treadmill and “push mode” walking.
In this experiment, participants were able to walk 3 times faster in the “push mode” and 2.6 times faster during treadmill walking as compared to their overground self-selected comfortable walking pace. Other researchers have done similar comparisons, Tyrell et al.  reported walking speeds that were 1.6 times faster than the participants’ self-selected walking pace overground, and Brouwer et al.  and Bayat et al.  showed speeds 1.2 times faster. We understand that these changes should not be used as direct comparisons because of the inherent differences between each study. Yet, we use this as an indicator of a possible factor that yields the results of our study.
The interpretation of results for this study may be limited by several factors. First, the spatiotemporal parameters measured in this experiment, average step length and cadence, were calculated from the recorded time and steps that participants generated to complete the 5-meter distance. Therefore, the data in this experiment do not provide for individual limb differences or allow for further comparison between stance and swing phases for each leg. However, the average step lengths reported in this experiment are similar to those reported by previous studies [16, 33]. Future research that expands and compares the current results with more specific spatiotemporal measurements is needed.
Second, some participants stopped the experiment due to an increased concern or fear of falling. In order to reduce the incidence of this behavior, we provided practice with the safety harness and further verbal encouragement during all trials. For example, once participants expressed their concern they were encouraged to sit on the harness, on both the treadmill and the robotic device, to assure them that they were in a safe environment and reduce their anxiety. In the end, every individual decided if they wanted to continue with the testing procedures. Therefore, we propose that these participants did not reach their maximum walking speeds due to psychological constraints and not because of physical or physiological limitations. The result of psychological stressors on behaviors such as walking is recognized but not widely studied. Thus, it is important that this subgroup is studied and acknowledged during experiments that test individuals at maximum walking speed. We suggest that, in order to study fast walking speeds in this subgroup of post-stroke individuals, attempts at repeated exposure to simplified fast walking tasks where the cognitive load is reduced may result in greater acceptability to move at faster speeds.
Third, equipment constraints possibly limited the ability of participants to reach faster walking speeds. During treadmill walking at fast speeds the width of the treadmill belt was a limiting factor. Participants confined their base of support (step width) within the width of the treadmill in order to avoid tripping and possibly losing balance. For those subjects whose step width seemed to increase with faster walking speeds, this task was troublesome. On the other hand, during overground fast walking speeds in the “push mode”, the robotic device did not maintain a straight line. Consequently, this resulted in longer distances walked in the “push mode” than on the treadmill. These longer walking distances could be due to the individuals’ asymmetry in the walking pattern or asymmetry in force production, among other factors. Future research, evaluating and comparing these two walking environments are needed, as well as careful and detailed studies of the kinetic and kinematic changes at maximal walking speeds.
The results of this study demonstrated that, after stroke, individuals have the capacity to walk at faster speeds than their overground self-selected maximum walking speed, while walking on a treadmill and in a robotic device. Moreover, in many cases participants were able to match the top speed limit of the robotic device (2.0 m/sec) which indicates that they may have been able to walk at even greater speeds. These changes in walking speed were obtained by initially increasing both step length and cadence. But, once individuals reached the limit of their step length, the only available option was to increase cadence. Therefore, at fast walking speeds step length became a limiting factor to achieve faster speeds during treadmill and “push mode” walking. These results support the growing body of evidence that shows the feasibility and benefits of training this population at high walking speeds.
CC carried out data collection, analysis and drafted the manuscript. CM assisted in data collection, completed subject recruitment, and helped draft the manuscript. DB participated in the design of the study, statistical analysis, and drafting the manuscript. All authors read and approved the final manuscript.
CC was supported in part by a scholarship from the Foundation for Physical Therapy, Inc. and by the Initiative to Maximize Student Development (IMSD) #R25GM079300. DB was supported in part by the U.S. Department of Education, National Institute on Disability and Rehabilitation Research (NIDRR) #H133E070013.
Funding was provided in part by a scholarship from the Foundation for Physical Therapy, Inc., and IMSD grant #R25GM079300, and by the U.S. Department of Education, National Institute on Disability and Rehabilitation Research (NIDRR) #H133E070013.
- Bohannon RW: Walking after stroke: comfortable versus maximum safe speed. Int J Rehabil Res 1992, 15: 246-248. 10.1097/00004356-199209000-00009View ArticlePubMedGoogle Scholar
- Turnbull GI, Charteris J, Wall JC: A comparison of the range of walking speeds between normal and hemiplegic subjects. Scand J Rehabil Med 1995, 27: 175-182.PubMedGoogle Scholar
- Jonsdottir J, Recalcati M, Rabuffetti M, Casiraghi A, Boccardi S, Ferrarin M: Functional resources to increase gait speed in people with stroke: strategies adopted compared to healthy controls. Gait Posture 2009, 29: 355-359. 10.1016/j.gaitpost.2009.01.008View ArticlePubMedGoogle Scholar
- Jonkers I, Delp S, Patten C: Capacity to increase walking speed is limited by impaired hip and ankle power generation in lower functioning persons post-stroke. Gait Posture 2009, 29: 129-137. 10.1016/j.gaitpost.2008.07.010PubMed CentralView ArticlePubMedGoogle Scholar
- Bohannon RW: Comfortable and maximum walking speed of adults aged 20–79 years: reference values and determinants. Age Ageing 1997, 26: 15-19.View ArticlePubMedGoogle Scholar
- Kollen B, Kwakkel G, Lindeman E: Hemiplegic gait after stroke: is measurement of maximum speed required? Arch Phys Med Rehabil 2006, 87: 358-363. 10.1016/j.apmr.2005.11.007View ArticlePubMedGoogle Scholar
- Farinatti PT, Monteiro WD: Walk-run transition in young and older adults: with special reference to the cardio-respiratory responses. Eur J Appl Physiol 2010, 109: 379-388. 10.1007/s00421-010-1366-1View ArticlePubMedGoogle Scholar
- Beaman CB, Peterson CL, Neptune RR, Kautz SA: Differences in self-selected and fastest-comfortable walking in post-stroke hemiparetic persons. Gait Posture 2010, 31: 311-316. 10.1016/j.gaitpost.2009.11.011PubMed CentralView ArticlePubMedGoogle Scholar
- Bayat R, Barbeau H, Lamontagne A: Speed and temporal-distance adaptations during treadmill and overground walking following stroke. Neurorehabil Neural Repair 2005, 19: 115-124. 10.1177/1545968305275286View ArticlePubMedGoogle Scholar
- Lamontagne A, Fung J: Faster is better: implications for speed-intensive gait training after stroke. Stroke 2004, 35: 2543-2548. 10.1161/01.STR.0000144685.88760.d7View ArticlePubMedGoogle Scholar
- Miller EW, Combs SA, Fish C, Bense B, Owens A, Burch A: Running training after stroke: a single-subject report. Phys Ther 2008, 88: 511-522. 10.2522/ptj.20050240View ArticlePubMedGoogle Scholar
- Pohl M, Mehrholz J, Ritschel C, Ruckriem S: Speed-dependent treadmill training in ambulatory hemiparetic stroke patients: a randomized controlled trial. Stroke 2002, 33: 553-558. 10.1161/hs0202.102365View ArticlePubMedGoogle Scholar
- Wada Y, Kondo I, Sonoda S, Miyasaka H, Teranishi T, Nagai S, Saitoh E: Preliminary trial to increase gait velocity with high speed treadmill training for patients with hemiplegia. Am J Phys Med Rehabil 2010, 89: 683-687. 10.1097/PHM.0b013e3181e29d27View ArticlePubMedGoogle Scholar
- Outermans JC, van Peppen RP, Wittink H, Takken T, Kwakkel G: Effects of a high-intensity task-oriented training on gait performance early after stroke: a pilot study. Clin Rehabil 2010, 24: 979-987. 10.1177/0269215509360647View ArticlePubMedGoogle Scholar
- Kuys SS, Brauer SG, Ada L: Higher-intensity treadmill walking during rehabilitation after stroke in feasible and not detrimental to walking pattern or quality: a pilot randomized trial. Clin Rehabil 2011, 25: 316-326. 10.1177/0269215510382928View ArticlePubMedGoogle Scholar
- Tyrell CM, Roos MA, Rudolph KS, Reisman DS: Influence of systematic increases in treadmill walking speed on gait kinematics after stroke. Phys Ther 2011, 91: 392-403. 10.2522/ptj.20090425PubMed CentralView ArticlePubMedGoogle Scholar
- Novacheck TF: The biomechanics of running. Gait Posture 1998, 7: 77-95. 10.1016/S0966-6362(97)00038-6View ArticlePubMedGoogle Scholar
- Reisman DS, Wityk R, Silver K, Bastian AJ: Locomotor adaptation on a split-belt treadmill can improve walking symmetry post-stroke. Brain 2007, 130: 1861-1872. 10.1093/brain/awm035PubMed CentralView ArticlePubMedGoogle Scholar
- Kahn JH, Hornby TG: Rapid and long-term adaptations in gait symmetry following unilateral step training in people with hemiparesis. Phys Ther 2009, 89: 474-483. 10.2522/ptj.20080237PubMed CentralView ArticlePubMedGoogle Scholar
- Chen G, Patten C, Kothari DH, Zajac FE: Gait differences between individuals with post-stroke hemiparesis and non-disabled controls at matched speeds. Gait Posture 2005, 22: 51-56. 10.1016/j.gaitpost.2004.06.009View ArticlePubMedGoogle Scholar
- Balasubramanian CK, Neptune RR, Kautz SA: Variability in spatiotemporal step characteristics and its relationship to walking performance post-stroke. Gait Posture 2009, 29: 408-414. 10.1016/j.gaitpost.2008.10.061PubMed CentralView ArticlePubMedGoogle Scholar
- Arene N, Hidler J: Understanding motor impairment in the paretic lower limb after a stroke: a review of the literature. Top Stroke Rehabil 2009, 16: 346-356. 10.1310/tsr1605-346View ArticlePubMedGoogle Scholar
- Roerdink M, Beek PJ: Understanding inconsistent step-length asymmetries across hemiplegic stroke patients: impairments and compensatory gait. Neurorehabil Neural Repair 2011, 25: 253-258. 10.1177/1545968310380687View ArticlePubMedGoogle Scholar
- Balasubramanian CK, Bowden MG, Neptune RR, Kautz SA: Relationship between step length asymmetry and walking performance in subjects with chronic hemiparesis. Arch Phys Med Rehabil 2007, 88: 43-49. 10.1016/j.apmr.2006.10.004View ArticlePubMedGoogle Scholar
- Kuys SS, Brauer SG, Ada L, Russell TG: Increasing intensity during treadmill walking does not adversely affect walking pattern or quality in newly-ambulating stroke patients: an experimental study. Aust J Physiother 2008, 54: 49-54. 10.1016/S0004-9514(08)70066-7View ArticlePubMedGoogle Scholar
- Yang F, Espy D, Pai YC: Feasible stability region in the frontal plane during human gait. Ann Biomed Eng 2009, 37: 2606-2614. 10.1007/s10439-009-9798-7PubMed CentralView ArticlePubMedGoogle Scholar
- Bhatt T, Wening JD, Pai YC: Influence of gait speed on stability: recovery from anterior slips and compensatory stepping. Gait Posture 2005, 21: 146-156. 10.1016/j.gaitpost.2004.01.008View ArticlePubMedGoogle Scholar
- Pai Y-C, Patton J: Center of mass velocity-position predictions for balance control. J Biomech 1997, 30: 347-354. 10.1016/S0021-9290(96)00165-0View ArticlePubMedGoogle Scholar
- Lugade V, Lin V, Chou LS: Center of mass and base of support interaction during gait. Gait Posture 2011, 33: 406-411. 10.1016/j.gaitpost.2010.12.013View ArticlePubMedGoogle Scholar
- England SA, Granata KP: The influence of gait speed on local dynamic stability of walking. Gait Posture 2007, 25: 172-178. 10.1016/j.gaitpost.2006.03.003PubMed CentralView ArticlePubMedGoogle Scholar
- Patton J, Brown DA, Peshkin M, Santos-Munne JJ, Makhlin A, Lewis E, Colgate JE, Schwandt D: KineAssist: design and development of a robotic overground gait and balance therapy device. (State of the Science Conference). Topics in Stroke Rehabilitation 2008,15(139):131.View ArticlePubMedGoogle Scholar
- Peshkin M, Brown DA, Santos-Munne JJ, Makhlin A, Lewis E, Colgate JE, Patton J, Schwandt D: KineAssist: A robotic overground gait and balance training device. In 2005 Ieee 9th International Conference on Rehabilitation Robotics. New York: Ieee: International Conference on Rehabilitation Robotics ICORR; 2005:241-246.Google Scholar
- Brouwer B, Parvataneni K, Olney SJ: A comparison of gait biomechanics and metabolic requirements of overground and treadmill walking in people with stroke. Clin Biomech (Bristol, Avon) 2009, 24: 729-734. 10.1016/j.clinbiomech.2009.07.004View ArticleGoogle Scholar
- Puh U, Baer GD: A comparison of treadmill walking and overground walking in independently ambulant stroke patients: a pilot study. Disabil Rehabil 2009, 31: 202-210. 10.1080/09638280801903039View ArticlePubMedGoogle Scholar
- Lee SJ, Hidler J: Biomechanics of overground vs. treadmill walking in healthy individuals. J Appl Physiol 2008, 104: 747-755. 10.1152/japplphysiol.01380.2006View ArticlePubMedGoogle Scholar
- Parvataneni K, Ploeg L, Olney SJ, Brouwer B: Kinematic, kinetic and metabolic parameters of treadmill versus overground walking in healthy older adults. Clin Biomech (Bristol, Avon) 2009, 24: 95-100. 10.1016/j.clinbiomech.2008.07.002View ArticleGoogle Scholar
- Prosser LA, Stanley CJ, Norman TL, Park HS, Damiano DL: Comparison of elliptical training, stationary cycling, treadmill walking and overground walking. Electromyographic patterns. Gait Posture 2011, 33: 244-250. 10.1016/j.gaitpost.2010.11.013PubMed CentralView ArticlePubMedGoogle Scholar
- Harris-Love ML, Forrester LW, Macko RF, Silver KH, Smith GV: Hemiparetic gait parameters in overground versus treadmill walking. Neurorehabil Neural Repair 2001, 15: 105-112. 10.1177/154596830101500204View ArticlePubMedGoogle Scholar
- Harris-Love ML, Macko RF, Whitall J, Forrester LW: Improved hemiparetic muscle activation in treadmill versus overground walking. Neurorehabil Neural Repair 2004, 18: 154-160. 10.1177/0888439004267678View ArticlePubMedGoogle Scholar
- Kautz SA, Bowden MG, Clark DJ, Neptune RR: Comparison of motor control deficits during treadmill and overground walking poststroke. Neurorehabil Neural Repair 2011, 25: 756-765. 10.1177/1545968311407515PubMed CentralView ArticlePubMedGoogle Scholar
- Burgess JK, Weibel GC, Brown DA: Overground walking speed changes when subjected to body weight support conditions for nonimpaired and post stroke individuals. J Neuroeng Rehabil 2010, 7: 6. 10.1186/1743-0003-7-6PubMed CentralView ArticlePubMedGoogle Scholar
- Patton JL, Brown DA, Lewis E, Crombie G, Santos J, Makhlin A, Colgate JE, Peshkin M: Motility evaluation of a novel overground functional mobility tool for post stroke rehabilitation. Proceedings of the IEEE 10th International Conference on Rehabilitation Robotics 2007, 1049-1054. [http://0-www.biomedcentral.com.brum.beds.ac.uk/content/pdf/1743-0003-7-6.pdf]Google Scholar
- Hill KH, Harburn KL, Kramer JF, Noh S, Vandervoort AA, Matheson JM: Comparison of balance responses to an external perturbation test, with and without an overhead harness safety system. Gait and Posture 1994, 2: 27-31. 10.1016/0966-6362(94)90014-0View ArticleGoogle Scholar
- Delbaere K, Sturnieks DL, Crombez G, Lord SR: Concern about falls elicits changes in gait parameters in conditions of postural threat in older people. J Gerontol A Biol Sci Med Sci 2009, 64: 237-242.View ArticlePubMedGoogle Scholar
- Gage WH, Sleik RJ, Polych MA, McKenzie NC, Brown LA: The allocation of attention during locomotion is altered by anxiety. Exp Brain Res 2003, 150: 385-394.PubMedGoogle Scholar
- Chamberlin ME, Fulwider BD, Sanders SL, Medeiros JM: Does fear of falling influence spatial and temporal gait parameters in elderly persons beyond changes associated with normal aging? J Gerontol A Biol Sci Med Sci 2005, 60: 1163-1167. 10.1093/gerona/60.9.1163View ArticlePubMedGoogle Scholar
- Hadjistavropoulos T, Delbaere K, Fitzgerald TD: Reconceptualizing the role of fear of falling and balance confidence in fall risk. J Aging Health 2011, 23: 3-23. 10.1177/0898264310378039View ArticlePubMedGoogle Scholar
- Legters K: Fear of falling. Phys Ther. 2002, 82: 264-272.PubMedGoogle Scholar
- Murphy J, Isaacs B: The post-fall syndrome. A study of 36 elderly patients. Gerontology 1982, 28: 265-270. 10.1159/000212543View ArticlePubMedGoogle Scholar
- Watt JR, Franz JR, Jackson K, Dicharry J, Riley PO, Kerrigan DC: A three-dimensional kinematic and kinetic comparison of overground and treadmill walking in healthy elderly subjects. Clin Biomech (Bristol, Avon) 2010, 25: 444-449. 10.1016/j.clinbiomech.2009.09.002View ArticleGoogle Scholar
- Nadeau S, Arsenault AB, Gravel D, Bourbonnais D: Analysis of the clinical factors determining natural and maximal gait speeds in adults with a stroke. Am J Phys Med Rehabil 1999, 78: 123-130. 10.1097/00002060-199903000-00007View ArticlePubMedGoogle Scholar
- Bohannon RW, Andrews AW: Correlation of knee extensor muscle torque and spasticity with gait speed in patients with stroke. Arch Phys Med Rehabil 1990, 71: 330-333.PubMedGoogle Scholar
- Nakamura R, Watanabe S, Handa T, Morohashi I: The relationship between walking speed and muscle strength for knee extension in hemiparetic stroke patients: a follow-up study. Tohoku J Exp Med 1988, 154: 111-113. 10.1620/tjem.154.111View ArticlePubMedGoogle Scholar
- Hall AL, Peterson CL, Kautz SA, Neptune RR: Relationships between muscle contributions to walking subtasks and functional walking status in persons with post-stroke hemiparesis. Clin Biomech (Bristol, Avon) 2011, 26: 509-515. 10.1016/j.clinbiomech.2010.12.010PubMed CentralView ArticleGoogle Scholar
- Olney SJ, Griffin MP, McBride ID: Temporal, kinematic, and kinetic variables related to gait speed in subjects with hemiplegia: a regression approach. Phys Ther 1994, 74: 872-885.PubMedGoogle Scholar
- Peterson CL, Hall AL, Kautz SA, Neptune RR: Pre-swing deficits in forward propulsion, swing initiation and power generation by individual muscles during hemiparetic walking. J Biomech 2010, 43: 2348-2355. 10.1016/j.jbiomech.2010.04.027PubMed CentralView ArticlePubMedGoogle Scholar
- Kim CM, Eng JJ: The relationship of lower-extremity muscle torque to locomotor performance in people with stroke. Phys Ther 2003, 83: 49-57.PubMedGoogle Scholar
- Suzuki K, Imada G, Iwaya T, Handa T, Kurogo H: Determinants and predictors of the maximum walking speed during computer-assisted gait training in hemiparetic stroke patients. Arch Phys Med Rehabil 1999, 80: 179-182. 10.1016/S0003-9993(99)90117-XView ArticlePubMedGoogle Scholar
- Lin PY, Yang YR, Cheng SJ, Wang RY: The relation between ankle impairments and gait velocity and symmetry in people with stroke. Arch Phys Med Rehabil 2006, 87: 562-568. 10.1016/j.apmr.2005.12.042View ArticlePubMedGoogle Scholar
- Richards CL, Olney S: Hemiparetic gait following stroke, part II: recovery and physical therapy. Gait and Posture 1996, 4: 149-162. 10.1016/0966-6362(96)01064-8View ArticleGoogle Scholar
- Bohannon RW: Selected determinants of ambulatory capacity in patients with hemiplegia. Clin Rehabil 1989, 3: 47-53. 10.1177/026921558900300107View ArticleGoogle Scholar
- Bohannon RW: Strength of lower limb related to gait velocity and cadence in stroke patients. Physiother Can 1986, 38: 204-206. 10.3138/ptc.38.4.204View ArticleGoogle Scholar
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