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Table 6 Results for the eight least addressed domains classified according to EXO and time since injury

From: Overground robotic training effects on walking and secondary health conditions in individuals with spinal cord injury: systematic review

  

Study

Robot Data

Bowel functionality

Strength

Activities of Daily Living

Neurophysiology

Sensory function

Bladder functionality

Body composition and bone density

Exoskeleton: Ekso

Subacute

n-RCT

Tsai et al. 2020

Each session: up time, walk time and steps number: not compared

 

Post vs Pre training: LEMS ↑, UEMS ↑

Post vs Pre training: FIM ↑

    

McIntosh et al. 2020

Longitudinal evaluation: up time , walk time , steps number

       

Chronic

RCT

Chang et al. 2018

  

Post vs Pre training: LEMS ↑

     

n-RCT

Gagnon et al. 2018 (A)

Longitudinal evaluation: up time ; walk time ; steps number

       

Escalona et al. 2018

        

Sale et al. 2016 (A)

 

Post vs Pre training: satisfaction questionnaire (single bowel item) ↑

      

Alamro et al. 2018

    

Single evaluation:

trunk muscle's activation: Ekso-OG > Lokomat

   

Karelis et al. 2017

       

Post vs Pre training: BMI ↑; Body weight ↑; leg and appendicular lean body mass ↑; Total, appendicular and leg fat mass ↓; Cross-sectional area of calf Muscle ↑; Total, arm, trunk lean body mass ↑, Arm fat mass ↓, Trunk fat mass nc, Total bone mineral density ↓, Leg and tibia bone mineral density ↑, Cross-sectional area: Subcutaneous and intramuscular adipose tissue ↓

Ramanujam et al. 2018 (A)

    

Single evaluation:

EMG lower limbs: SCI < ABs

   

Gagnon et al. 2019 (B)

        

Ramanujam et al. 2018 (B)

        

Kressler et al. 2014 (A)

    

Post vs Mid vs Pre training: EMG nc

   

Kressler et al. 2019 (B)

        

Cahill et al. 2018

        

Subacute + chronic

n-RCT

Baunsgaard et al. 2018 (A)

Subacute:

Longitudinal evaluation: up time , walk time , steps

 

Subacute: Post vs Pre training and FU vs Pre training:

LEMS ↑

     

Chronic: Longitudinal evaluation: up time , walk time , steps

 

Chronic: Post vs Pre training and FU vs Pre training: LEMS ↑

     

Baunsgaard et al. 2018 (B)

 

FU vs Post vs Mid vs Pre training: ISCIBDS nc

 

Post vs Pre training and FU vs Pre training: SCIM III > 

  

FU vs Post vs Mid vs Pre training: ISCIBDS nc

 

Stampacchia et al. 2016

        

Kozlowski et al. 2015

Best performance: walk time, up time, steps number

       

Kolakowsky-Hayner et al. 2013

Longitudinal evaluation: up time , walk time

       

Unspecified TSI

n-RCT

Sale et al. 2018 (B)

 

Post vs Pre training: Satisfaction questionnaire (single bowel item)

      

Exoskeleton: ReWalk

Chronic

n-RCT

Asselin et al. 2015

        

Khan et al. 2019

Londitudinal evaluation: total steps number

 

Post vs Pre training: UEMS ↑, LEMS ↑

 

Post vs Pre training: MEP ↓

Post vs Pre training: sensory key-points INSCSCI nc

  

Platz et al. 2016

  

Post vs Pre training: LEMS nc; UEMS nc

Post vs Pre training: SCIM nc

 

Post vs Pre training: sensory score INSCSCI nc

  

van Dijsseldonk et al. 2019

        

Chun et al. 2020

 

Post vs Pre training: Modified Lynch Gastrointestinal Survey: frequency of bowel evacuations nc, time spent on having a bowel movement nc, bowel accidents ↑, frequency of laxative and/or stool softener use ↑, overall satisfaction with bowel programs ↑;

Bristol Stool Scale: stool consistency rated “ideal”↑;

SCI-QOL ↓

      

Yang et al. 2015

        

Benson et al. 2016

        

Fineberg et al. 2013

        

Guanziroli et al. 2019

        

Zeilig et al. 2012

 

Single evaluation Post training: Satisfaction Questionnaire (single bowel item) nc

      

Esquenazi et al. 2012

 

Single evaluation Post training: Satisfaction Questionnaire (bowel regulation) ↑ for 5/11 individuals

      

Lonini et al. 2016

Longitudinal evaluation: step frequency and steps number (positive correlation with session)

       

Manns et al. 2019

 

Single evaluation Post training: semi structured interview faster and more regular bowel movements for 3/11 individuals;

FU: semi structured interview faster and more regular bowel movements for 1/11 individuals

      

Talaty et al. 2013

        

Exoskeleton: Indego

Chronic

n-RCT

Evans et al. 2015

        

Subacute + chronic

n-RCT

Juszczak et al. 2018

 

Post vs Pre training: Self reported perception: 80% individuals nc, 20% individuals ↑

    

Pre vs Post training: Self reported perception: 91% individuals nc, 9% individuals ↑

 

Unspecified TSI

n-RCT

Tefertiller et al. 2018

        

Hartigan et al. 2015

        

Exoskeleton: HAL

Subacute

n-RCT

Yatsugi et al. 2018

   

Post vs Pre training: BI ↑

    

Kubota et al. 2019

  

Post vs Pre training: LEMS↑

Post vs Pre training: FIM ↑

    

Exoskeleton: Rex

Chronic

n-RCT

Birch et al. 2017

        
  1. Studies results are hierarchically reported according to the D&B total score. The type of comparison is specified within cells. In case of an increase of the data between evaluation time points “↑” is reported, while in case of a reduction of the data between evaluation time points “↓” is reported. In case of longitudinal evaluations during the training sessions "" is reported to indicate a progressive increase of the data while "" is reported to indicate a progressive reduction of the data. In case of comparison between groups or between different experimental conditions " > " or " < " are used. If no changes are reported “nc” is used. If the Authors of the study identified significant data variations, results are reported in bold characters. Italics cells indicate that evaluations were performed with the individuals wearing the EXO. For abbreviations see the Abbreviation List