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Table 4 Performance characteristics of corrected slack angle and slack angle for classifying different severity of spasticity based on optimal cutoff values

From: Reliability and diagnostic accuracy of corrected slack angle derived from 2D-SWE in quantitating muscle spasticity of stroke patients

Method

MAS ≥ 1+ (95% CI)

MAS ≥ 2 (95% CI)

MAS ≥ 3 (95% CI)

Corrected slack angle

 Cutoff value

3.75

− 6.75

− 10.25

 AUROC

0.906 (0.691–0.990)

0.920 (0.709–0.993)

0.987 (0.808–1.000)

 Sensitivity (%)

93.75 (69.8–99.8)

80.00 (44.4–97.5)

100.00 (47.8–100.0)

 Specificity (%)

75.00 (19.4–99.4)

90.00 (55.5–99.7)

93.33 (68.1–99.8)

 PPV (%)

93.7 (68.6–99.9)

88.9 (48.9–99.8)

83.3 (31.1–99.8)

 NPV (%)

75.0 (13.2–99.8)

81.8 (46.3–98.1)

100.0 (76.8–100.0)

 LR+

3.75 (2.1–6.7)

8.00 (5.5–11.6)

15.00 (13.1–17.2)

 LR−

0.083 (0.007–1.1)

0.22 (0.02–2.1)

0

Slack angle

 Cutoff value

0.25

− 3.25

− 6.75

 AUC

0.617 (0.377–0.822)

0.605 (0.365–0.813)

0.620 (0.379–0.824)

 Sensitivity (%)

93.75 (69.8–99.8)

80.00 (44.4–97.5)

80.00 (28.4–99.5)

 Specificity (%)

50.00 (6.8–93.2)

50.00 (18.7–81.3)

60.00 (32.3–83.7)

 PPV (%)

88.2 (62.6–98.7)

61.5 (31.6–86.1)

2.00 (1.1–3.7)

 NPV (%)

66.7 (4.0–99.8)

71.4 (25.8–97.2)

0.33 (0.05–2.1)

 LR+

1.87 (0.7–5.0)

1.60 (0.8–3.2)

40.0 (12.2–73.8)

 LR−

0.13 (0.01–1.1)

0.40 (0.1–1.6)

90.0 (53.0–99.8)

  1. Data in parentheses are 95% confidence intervals
  2. MAS modified Ashworth scale, AUROC area under the receiver operator characteristic curve, PPV positive predictive value, NPV negative predictive value, LR+ positive likelihood ratio, LR− negative likelihood ratio