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Fig. 7 | Journal of NeuroEngineering and Rehabilitation

Fig. 7

From: Epidural cerebellar stimulation drives widespread neural synchrony in the intact and stroke perilesional cortex

Fig. 7

Activity in post-stroke peri-infarct M1 during cerebellar stimulation. a A schematic of electrophysiological recordings in stroke peri-infarct M1 and cerebellar stimulation (left). A histology image with Fluoro-Jade C staining showing the sagittal view of stroke area and the site of electrophysiologcal recordings. b Mean Stimpre firing rate of intact and stroke animals is shown as mean ± s.e.m. (Str: stroke; **p < 5 × 10-8). c An example peri-infarct M1 unit showing modulation during stimulation (bottom). Its waveform and inter-spike interval histogram is also shown. d Violin plot showing firing rate change between Stimpre and Stimdur across all high-SNR peri-infarct M1 units. e Representative cross-correlogram of a pair of peri-infarct M1 units, before and during cerebellar stimulation (left). Mean change in ΔCCH is shown as mean ± s.e.m., across four animals (right). f An example LFP power from a single animal before and during cerebellar stimulation (left). Grey shaded area shows the slow frequency band (0.3–4 Hz). The average LFP power in the slow frequency band across four animals is shown on the right side, *p < 1 × 10–2

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