Table 1 Inclusion and exclusion criteria

Original articles describing the design of a digital application specifically for health contexts (e.g. reducing symptoms, recovering body or cognitive functions, or maintaining health)

Use a HMD-VR as the display and interaction technology

Describes the VR application as a game

Available in the English language

Published in peer reviewed academic or professional journals

Only used commercially available HMD-VR games designed for general audiences

Opinion or narrative discussions that did not report on the use of a specific VR-based game

Grey literature