Exploring the effects of deep brain stimulation and vision on tremor in Parkinson’s disease - benefits from objective methods

Table 2 UPDRS values

UPDRS part III scores, without anti-PD medication	DBS turned OFF	DBS turned ON
20: Face lips	0.2 (0.6)	0.0 (0.0)
20: Right hand	0.9 (1.2)	0.0 (0.0)
20: Left hand	0.8 (1.1)	0.0 (0.0)
20: Right foot	0.6 (1.0)	0.0 (0.0)
20: Left foot	0.7 (1.2)	0.0 (0.0)
21 Action right hand	0.2 (0.4)	0.0 (0.0)
21 Action left hand	0.6 (1.0)	0.0 (0.0)
Item 20 & 21 (tremor)	3.9 (4.5)	0.0 (0.0)
Total UPDRS Score	48.0 (15.7)	20.6 (6.1)

(SD) values are presented
UPDRS part III: Unified Parkinson’s disease Rating Scale, motor examination. The maximum total score on the UPDRS part III is 108 points, and higher scores reflect more severe motor symptoms.
Item 20 of UPDRS part III assesses rest tremor in A) the face, lips and chin (scored 0–4), B) hands (right and left, each scored from 0 to 4), and C) feet (right and left, each scored from 0 to 4). Item 21 assesses action or postural tremor in the hands (right and left, each scored from 0 to 4).
Without medication: Overnight withdrawal of all anti-Parkinsonian medication for 10–12 h. All individuals were on L-dopa, and seven out of the ten participants were also on dopamine agonists (ranging from 20 to 50% of L-dopa equivalent dose). When tested, all participants experienced clinical off symptoms.
The UPDRS assessments were done at the same occasion as the physical assessments of tremor.

ISSN: 1743-0003