Table 2 Summary of the results of the chronic in vivo studies in animals, with the LIFE, SELINE and regenerative electrodes
From: Interfaces with the peripheral nervous system for the control of a neuroprosthetic limb: a review
Interface | Longevity |
|---|---|
LIFE | A life-time of 18-24 months is expected [179]; slight tissue damage in the early phase but normalizes after 6 months [180] |
SELINE | Inflammatory response in the early phase, but stable after 6 months [181] |
Regenerative electrodes | Inflammatory response to nerve transection, but good signal quality after 4 months [182]; another 12-month study observed regeneration and reliable signals in the first 6 months, but axonal damage and functional decline in the second 6 months [183] |