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Table 4 Examples of stimulation parameters in literature

From: Safety of long-term electrical peripheral nerve stimulation: review of the state of the art

Publication

Subjects

Electrode type

Stimulation/ Recording

Electrode Placement

Treatment Duration (Y)

Purpose of Stimulation

Stimulation Parameters

Charge of Stimulating Phase (Q)

Current of Stimulating Phase (I)

Duration of Stimulating Phase (D)

Stimulation Frequency (F)

Train Duration (T)

Effective Stimulation Time per Day (S)

Potential Stimulation Time per Day (P)

Percentage of Effective Stimulation (O)

Waveform

Shape

Polarity

Symmetry

Inter-Phase Delay (w)

Electrical Stimulation for Sensory Feedback

 Clippinger et al. [57]

A

Cuff

S

M

<  2 y

S

c

0–100

 

 Anani et al. [97]

AB

Needle

S

M, R

<  1 d

S

<  200

250–2600

30–250

2.5–160

1

20

Rect.

M

 Walker et al. [115]

A

Cuff

S

M

3 y

S

c

20–640

0–90

2

24

8.3

 Anani and Körner [116]

AB

Needle

S

forearm

<  1 d

S

b

200

10–80

120

Rect.

a

 Anani and Körner [116]

A

Needle

S

M, R, U

<  1 d

S

40–300

400–3000

100

10–80

3–4

Rect.

a

 Ochoa and Torebjörk [95]

AB

Needle

S, R

M, U

<  1 d

S

c

250

1–300

2

3–6

Rect.

M

 Dhillon et al. [8]

A

LIFE

S, R

M, U, P

<  1 m

S

<  50

<  200

250

10–800

0.5

Rect.

M, B

A, S

 Dhillon and Horch [7]

A

LIFE

S, R

M

<  1 m

S

b

300

10–500

0.5

 Dhillon et al. [9]

A

LIFE

S, R

M

<  1 m

S

<  60

1–200

300

10–510

0.5

B

 Rossini et al. [10]

A

Tf-LIFE4

S, R

M, U

<  1 m

S

<  3

10–100

10–300

10–500

0.3–0.5

Rect.

 Horch et al. [11]

A

LIFE

S

M, U

<  2 w

S

b

290

20–200

B

75

 Clark et al. [12]

A

USEA

S, R

M, U

<  1 m

S

2–2.4

10–12

200

200

0.2

 Ortiz-Catalan et al. [18]

A

Cuff

S

U

20 m

S

100–180

8–30

B

 Raspopovic et al. [13]

A

TIME

S

M, U

<  1 m

S

<  24

240

100

50

0.5

Rect.

B

 Tan et al. [17]

A

FINE

S

M, R, U

16 m & 24 m

S

<  2000

20–167

1–1000

<  60

4–6

Rect

B

A

 Davis et al. [14]

A

USEA

S, R

M, U

<  1 m

S

0.2–20

1–100

200

1–320

0.2–60

2

B

100

 Graczyk et al. [19]

A

FINE

S

M, R, U

3 y & 4 y

S

b

<  255

12.5–166

1–5

Rect.

B

 Oddo et al. [15]

A

TIME

S

M

<  1 m

S

16

160

100

 Schiefer et al. [21]

A

FINE

S

M, R, U

2 y & 3 y

S

255

10–125

5–6

B

 Mastinu et al. [20]

A

Cuff

S

U

4 y

S

<  30

Rect.

B

A

50

 Ortiz-Catalan et al. [22]

A

Cuff

S

U

4 y

S

 Wendelken et al. [16]

A

Cuff

S, R

M, U

4–5 w

S

<  24

<  120

200

<  200

1–6

B

100

 Graczyk et al. [114]

A

FINE

S

M, R, U

5 y

S

300

<  255

25–299

<  3 min

< 6

Rect.

B

Electrical Stimulation for Motor Function, Pain Relief, or other purposes

 Nashold et al. [39]

CP

Cuff, Button

S

M, R, S, U

<  11 y

O

c

300

25–100

B

 Waters et al. [6]

P

Cuff

S

P

<  12 y

M

c

200

33

Rect.

 Ben-Menachem et al. [83]

E

Cuff

S

V

14 w

O

250–3000

130–500

1–50

30–90

5–23

 Elefteriades et al. [5]

Q

Ribbon

S

Ph

<  18 y

M

15–690

100–4600

150

7.2–8.3

0.9–1.3

0.016–0.48

8–12

0.2–0.4

 Vandoninck et al. [117]

UI

Needle

S

T

<  1 d

O

4000

0–20,000

200

20

0.5

0.5

100?

 Fisher et al. [93]

SCI

Cuff

S

F

3 y

M

160–420

800–2100

200

20

760

B

 Abdellaoui et al. [118]

COPD

T

S

6000-18,800

15,000-47,000

400

35

3600

1

1

100

Rect.

B

S

 Christie et al. [26]

A, SCI

Cuff

S

A, F, Fi, LT, Mu, R, Su, Th, T

<  11 y

M, S

100–20,000

1–255

12.5–100

B

  1. Subjects: AB Able-bodied, A Amputee, COPD Chronic obstructive pulmonary disease, CP Chronic pain due to peripheral nerve injury, P Centrally paralyzed ankle dorsiflexor muscle, Q Quadriplegia, SCI Spinal cord injury, UI Urge incontinence
  2. Electrode types: Cuff, LIFE longitudinal intrafascicular electrode, Needle, Ribbontf-LIFE4 thin film longitudinal intrafascicular multielectrode, T transcutaneous electrode, TIME transversal intrafascicular multichannel electrode, USEA Utah Slanted Electrode Array
  3. S Stimulation, R Recording
  4. Electrode Placement: A axillary, F femoral, Fi fibular, LT long thoracic, M median, Mu musculocutaneous, P peroneal, Ph phrenic, R radial, S sciatic, Su suprascapular, Th thoracodorsal, T tibial, U ulnar
  5. Purpose of Stimulation: M motor function, O other, S sensory feedback
  6. Stimulation Parameters: see Tables 1 and 2
  7. Waveform: Shape: Rect Rectangular
  8. Polarity: M Monophasic, B Bipphasic
  9. Symmetry: S Symmetric, A Asymmetric
  10. a- continuous pattern
  11. b − individually determined, no specification
  12. c − voltage modulation