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Table 1 Specific categories along with the illustrative diagnoses, numbers in each group, mean age, gender and functional scores represented by the Rivermead Mobility Index (RMI) for each category

From: Co-activation: its association with weakness and specific neurological pathology

Category

Illustrative specific diagnoses

Mean (SD) age in years; Gender: male/female

Median (range) RMI

Control mean (SD) age in years; Gender: male/female

Primary muscle or neuromuscular junction disorder (n = 17)

Muscular dystrophy (n = 9)

Polymyositis (n = 5)

Myasthenic syndrome (n = 1)

Acid-maltase deficiency (n = 1)

Familial periodic paralysis (n = 1)

53.4 (12.4)

8 male, 9 female

12 (9 to 15)

51.7 (11.0)

8 male, 9 female (n = 17)

Peripheral nerve disorder with sensory loss (n = 18)

Guillain Barré syndrome (n = 9)

Chronic inflammatory demyelinating polyneuropathy or sensory/motor neuropathy (n = 7)

Axonal sensory/motor polyneuropathy (n = 1)

Sensory peripheral polyneuropathy (n = 1)

56.7 (13.9)

7 male, 11 female

11.5 (4 to 15)

56.7 (11.0)

7 male, 11 female (n = 18)

Lower motor neuron (LMN) disorder with no or minor sensory loss (n = 12)

Motor neuropathy (n = 3)

Motor neuron disease (clinical LMN signs only) (n = 3)

Spinal muscular atrophy (n = 5)

Lower motor neuron syndrome (n = 1)

52.9 (14.9)

10 male, 2 female

12 (4 to 15)

57.0 (13.5)

14 male; 9 female (n = 24)

Upper motor neuron lesions (UMN) (n = 12)

Hereditary spastic paraplegia Motor neuron disease with clinical UMN signs only (n = 1)

Pyramidal Adrenoleukodystrophy (manifesting carrier) (n = 1)

51.6 (11.6)

7 male, 5 female

11.5 (7 to 14)

56.8 (14.5)

14 male; 9 female (n = 24)

Extra-pyramidal disorder (n = 15)

Parkinson's disease (PD) (n = 15)

64.3 (10.4)

11 male, 4 female

14 (9 to 15)

64.7 (9.5)

11 male, 4 female