Table 2 Results on primary outcome measures

53 [47, 57]

52 [44, 58]

54 [51, 59]

53 [50.7, 59.5]

NS

50 [39, 58]

54 [45, 59]

55 [46, 56]

52 [43, 59]

NS

39 [28, 46]

43 [28, 49]

43 [32, 51]

50 [27, 54]

NS

31 [24, 40]

38 [24, 43]

34 [25, 41]

37 [25, 49]

** ^††T0-T2

2.2 [1.5, 3.8]

2.8 [1.5, 4.6]

3.7 [2.5, 4.2]

3.8 [1.7, 4.3]

** ^††T0-T1

2.2 [1.5, 2.8]

1.9 [1.4, 3.6]

2.2 [1.6, 4.2]

2.8 [2.2, 3.8]

ns

1.8 [0.9, 3]

2.7 [1, 3.5]

3 [2.2, 3.5]

2.3 [1.3, 4]

** ^{†† T0-T2 ††T0-T1}

1.5 [1.1, 2.1]

1.7 [0.9, 3.1]

1.6 [1.3, 3.4]

2 [1.6, 3.5]

** ^††T0-T2

4.1 [2.4, 6.9]

5.3 [2.5, 8.3]

6.1 [4.8, 7.8]

6.1 [3, 8.5]

** ^{††T0-T2 ††T0-T1}

3.7 [2.7, 4.9]

3.6 [3.6, 2.2, 7]

3.7 [3.6, 7.9]

5 [4, 7.4]

**

70 [64, 75]

-

78 [68, 90]

75 [60, 80]

NS

65 [63, 85]

-

80 [70, 80]

74 [70, 80]

NS

59 [519, 65.4]

-

71 [59.4, 92]

64 [52.8, 84.3]

** ^{††T0-T2 †† T2-T3}

58.4 [38.9, 64.9]

-

58.4 [55, 70]

64 [58.4, 77]

NS

84.5 [74.8, 95.25]

-

87.6 [72.6, 98.7]

86.6 [75.2, 100]

NS

86.5 [81.6, 90.5]

-

86.7 [81.7, 91.3]

82.7 [76.3, 91.2]

NS