Table 2 Effects of DBS on motor symptoms and single-task, usual-walking gait
From: Impact of sub-thalamic nucleus deep brain stimulation on dual tasking gait in Parkinson’s disease
OFF meds | ON meds | |||||
|---|---|---|---|---|---|---|
OFF DBS | ON DBS | P-value OFF vs. ON DBS | OFF DBS | ON DBS | P-value OFF vs. ON DBS | |
UPDRS Motor part | 38.53 ± 13.53 | 17.5 ± 8.20 | <0.001 | 36.20 ± 13.84 | 13.40 ± 7.82* | <0.001 |
Timed Up and Go (sec) | 14.97 ± 5.69 | 12.62 ± 4.42 | 0.001 | 13.28 ± 3.27 | 11.46 ± 2.35* | 0.007 |
Gait speed (m/s) | 1.01 ± 0.30 | 1.09 ± 0.31 | 0.009 | 1.13 ± 0.19 | 1.21 ± 0.18* | 0.053 |
Stride length (m) | 1.09 ± 0.29 | 1.16 ± 0.30 | 0.005 | 1.27 ± 0.14 | 1.32 ± 0.15* | 0.049 |
Stride time (sec) | 1.10 ± 0.12 | 1.090 ± .10 | 0.502 | 1.09 ± 0.10 | 1.09 ± 0.10 | 0.653 |
Stride time variability (%) | 2.82 ± 1.42 | 2.33 ± 1.24 | 0.093 | 2.19 ± 0.91 | 1.84 ± 0.46* | 0.407 |
Swing time (%) | 36.19 ± 3.09 | 36.18 ± 2.68 | 0.654 | 36.66 ± 2.87 | 36.90 ± 2.05 | 0.199 |
Swing time variability (%) | 5.35 ± 3.10 | 4.65 ± 2.81 | 0.156 | 4.68 ± 2.02 | 3.94 ± 1.20 | 0.035 |